COVID-19 is an emerging, rapidly evolving situation.

Get the latest public health information from CDC:

Get the latest research information from NIH:

About offers access to the latest, federally approved HIV/AIDS medical practice guidelines, HIV treatment and prevention clinical trials, and other research information for health care providers, researchers, people affected by HIV/AIDS, and the general public., a service of the U.S. Department of Health and Human Services (HHS), is maintained by the Office of AIDS Research (OAR), which is part of the National Institutes of Health (NIH). OAR coordinates HIV/AIDS research across the National Institutes of Health (NIH). The NIH provides the largest public investment in HIV/AIDS research globally. is 100% federally funded and sponsored by the Office of AIDS Research (OAR).


The AIDS Clinical Trials Information Service (ACTIS) was mandated by the Health Omnibus Programs Extension Act (HOPE) in 1988. This legislation required the U.S. Food and Drug Administration (FDA) to provide a telephone reference service to disseminate HIV/AIDS clinical trials information to health professionals and the general public. ACTIS, which was created by an interagency team at NIAID, FDA, NLM, and CDC, opened in 1989. During the 11 years of its existence, the service responded to more than 225,000 telephone requests for HIV/AIDS clinical trials information. 

As new therapies and guidelines for the treatment of HIV/AIDS were approved, the need to provide up-to-date information in these areas became apparent. In 1994, six Public Health Service (PHS) agencies joined together to launch the HIV/AIDS Treatment Information Service (ATIS) as a vehicle to quickly convey this information to people living with HIV and health care providers. ATIS became the central dissemination point for the PHS treatment guidelines through the telephone reference service and the ATIS website. ATIS was supported by funding from many PHS agencies including NIH, the Health Care Financing Administration (HCFA, now the Centers for Medicare and Medicaid Services – CMS), CDC, and HRSA. 

ACTIS and ATIS were merged into a single information service, which became operational on December 1, 2002. The Spanish-language companion website, was launched in April 2007.

In September 2020 the Office of AIDS Research (OAR) transitioned the public and websites from the National Library of Medicine (NLM) to OAR and the Department of Health and Human Services (HHS) Office of Infectious Diseases and HIV/AIDS Policy (OIDP). The websites have been renamed and HIVinfo features the Understanding HIV components including easy-to-understand fact sheets and infographics. Clinical Info features the HIV Clinical Treatment Guidelines, the HIV Drug Database, and the Glossary. Both sites feature Spanish pages that can be accessed using the Spanish (es) dropdown.  

Disclaimer services and staff cannot replace direct communication with your health care provider(s). The staff cannot respond to specific medical questions, offer medical advice, give second opinions, or make recommendations about specific therapies.

HIVinfo neither allows advertising on the website, nor endorses any company or products.