What is a Therapeutic HIV Vaccine?
- A therapeutic HIV vaccine is a vaccine that is designed to improve the body’s immune response to HIV in a person who already has HIV.
- Currently, no therapeutic HIV vaccines have been approved by the U.S. Food and Drug Administration (FDA), but research is underway. You must be enrolled in a clinical trial to receive a therapeutic HIV vaccine.
- Researchers are exploring therapeutic HIV vaccines to slow down the progression of HIV infection and to eliminate the need for antiretroviral therapy (ART) while keeping undetectable levels of HIV.
Researchers are developing and testing therapeutic HIV vaccines to slow down the progression of HIV to acquired immunodeficiency syndrome (AIDS). The hope is that treating people with these vaccines would ideally keep HIV at undetectable levels (known as undetectable viral load) without the need for regular antiretroviral therapy (ART). ART is the recommended treatment for HIV infection and involves using a combination of different HIV medicines to prevent HIV from multiplying. Currently, a person with HIV must remain on ART to keep HIV at undetectable levels.
A therapeutic HIV vaccine may also make it less likely that a person could transmit HIV to others.
A preventive HIV vaccine is given to people who do not have HIV, with the goal of preventing HIV infection in the future. The vaccine teaches the person's immune system to recognize and effectively fight HIV in case the virus ever enters the person’s body. To learn more, read the HIVinfo What is a Preventive HIV Vaccine? fact sheet.
A therapeutic HIV vaccine is given to people who already have HIV. The goal of a therapeutic HIV vaccine is to strengthen a person’s immune response to the HIV that is already in the person's body.
A list of clinical trials on therapeutic HIV vaccines is available from the database of ClinicalTrials.gov study summaries. Click on the title of any trial in the list to see more information about the study.
If you are interested in participating in a vaccine study, you can also contact the National Institutes of Health Vaccine Research Center by calling 866-833-LIFE (5433) or by emailing firstname.lastname@example.org. To learn more, read the HIVinfo fact sheet on HIV and AIDS Clinical Trials.